Independent Pharmacy & AI Powered Marketplace = Match Made in Heaven

The MatchRx "This Week in Pharmacy" Series explores how independent pharmacies can strengthen their businesses, better serve patients, and remain competitive through smarter, more connected drug procurement.

MatchRx is a secure, online pharmacy marketplace that connects independent pharmacies to buy and sell non-controlled, non-expired overstock medications. This platform helps optimize inventory, reduce waste, lower costs, and source hard-to-find medications for specific patient needs.

Understanding the Pharmacy-to-Pharmacy Network

Operating as a Pharmacy-to-Pharmacy (P2P) network, MatchRx ensures safe, compliant drug transfers while meeting regulatory requirements, including the Drug Supply Chain Security Act (DSCSA). The platform also expands purchasing power by providing access to NABP-certified secondary wholesalers—all in one streamlined solution.

Transforming Inventory Management

Across three episodes, this series highlights how MatchRx’s growing network of more than 7,200 independent pharmacies is transforming inventory management and medication access nationwide. This transformation is especially crucial during ongoing drug shortages and supply chain disruptions.

On TWIRx, Johny Kello welcomes one of the 50 Most Influential People in Pharmacy, Ilisa B.G. Bernstein, PharmD, JD. Together, they break down the current state of DSCSA compliance as the industry approaches the critical November 2025 enforcement deadline. With decades of leadership in pharmacy practice, regulatory policy, and national advocacy, Dr. Bernstein brings unmatched clarity to what pharmacies must do now.

The Importance of Compliance

The right technology partnerships can keep pharmacies operational, efficient, and fully compliant. Johny and Dr. Bernstein discuss why DSCSA readiness remains one of the most pressing challenges for independent and community pharmacies. Topics include data verification, product tracing, and avoiding shipment rejections, workflow disruptions, and audit exposure.

The TrumpRx Playbook for Independent Pharmacies

CEO of MatchRx Johny Kello returns to TWIRx featuring our guest speaker, Dae Lee, Pharm.D., Esq., CPBS. Dae is a pharmacist-attorney and a Shareholder in the FDA & Biotechnology practice at Buchanan Ingersoll & Rooney. His unique perspective is invaluable because he represents pharmacies daily in high-stakes fights with PBMs. These include audits, reimbursement disputes, network suspensions, and terminations.

Navigating Legal Challenges

When we discuss TrumpRx—how it works, what it could break, and what independents should do next—Dae can translate the legal and contracting reality into real-world consequences behind the counter. His insights help pharmacies navigate the complexities of the current landscape.

Connect with MatchRX: MatchRX.com

Independent pharmacies are dispensing more prescriptions than ever—but too many are seeing their profits shrink month after month. In this episode of This Week in Pharmacy, hosts Todd Eury and CEO of MatchRx Johny Kello sit down with Saeed Dinno Pharmacist in Charge with Apotheco Pharmacy Group for a practical, plain-English breakdown of one of the most overlooked metrics impacting pharmacy profitability: GCR. This episode isn’t about policy debates, compliance theory, or vendor hype. It’s a real-world conversation designed to help pharmacy owners, managers, and buyers understand how everyday sourcing and dispensing behaviors directly influence margin—often without anyone realizing it.

Saeed explains what GCR actually measures, what it does not measure, and why two pharmacies filling the exact same prescription can end up with completely different financial outcomes. From convenience buying and emergency orders that become routine, to default NDC selection and a disconnect between the buyer and the bench, the episode highlights the subtle habits that quietly erode profitability over time.

More importantly, the conversation delivers actionable steps pharmacies can implement immediately. Saeed outlines the core disciplines that improve performance—smarter buying strategy, better alignment between purchasing and dispensing, and simple operational guardrails that don’t slow workflow. The focus is not on “working harder,” but on working differently.

The episode closes with a clear, clip-worthy takeaway: one specific action pharmacy leaders can take this month to start moving the needle.

Conclusion

In conclusion, the MatchRx "This Week in Pharmacy" Series is a vital resource for independent pharmacies. It offers insights into compliance, inventory management, and the evolving landscape of pharmacy practice. By staying informed and connected, pharmacies can navigate challenges and seize opportunities for growth.

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